A woman in her 60s with connective tissue disease and pulmonary arterial hypertension presented with new-onset ascites. She had jugular venous distension, an accentuated P2 on cardiac exam, ascites on exam, liver ultrasound characterized by irregular echo pattern, ascites protein level of 3.5 g/dL, and a serum-ascites albumin gradient of 1.5. What is the cause of her ascites?
This phase 2 study investigates the optimal dose and tolerability of vericiguat, a soluble guanylate cyclase stimulator, in patients with worsening chronic heart failure with reduced left ventricular ejection fraction.
This article from The Medical Letter reviews the recommendations and medications available to treat chronic heart failure.
This randomized clinical trial compares the effects of liraglutide vs placebo on time to death and rehospitalization and on time-averaged proportional change in N-terminal pro-B-type natriuretic peptide level among patients with heart failure and reduced left ventricular ejection fraction (LVEF) of 40% or lower.