Stroup and colleagues compare the efficacy failure rate of intramuscular injections of paliperidone palmitate palmitate vs haloperidol decanoate decanoate in a double-blind randomized clinical trial of 311 US adults with schizophrenia or schizoaffective disorder.
This Viewpoint focuses on research priorities to better understand and effectively respond to the Zika virus crisis.
This Viewpoint discusses issues related to the use of “provider” to describe primary care health professionals with varying levels of training and certification and the effects of these issues on quality of care.
This systematic review to support the 2016 US Preventive Services Task Force Recommendation Statement on screening for depression summarizes trial evidence about depression screening, treatment, and accuracy of screening instruments in pregnant and postpartum women.
This randomized trial reports that antenatal multiple micronutrient compared with iron–folic acid supplementation did not reduce infant mortality to age 6 months but resulted in a non–statistically significant reduction in stillbirths and significant reductions in preterm births and low birth weight.
In a trial involving 30 adult patients with sickle cell phenotype with or without thalassemia, Hsieh and coauthors report that after undergoing nonmyeloablative allogeneic hematopoietic stem cell transplantation from human leukocyte antigen–matched siblings, 26 patients achieved long-term engraftment.
Porsteinsson and colleagues evaluate the efficacy of citalopram for agitation in patients with Alzheimer disease in a randomized controlled trial comprising 186 patients with probable Alzheimer disease and clinically significant agitation from 8 US and Canadian centers, August 2009-January 2013.