Bezerra and coauthors report on the effect of high-dose corticosteroids following hepatoportoenterostomy on bile drainage in infants with biliary atresia.
This randomized clinical trial compares the effects of a below-knee cast vs surgery on ankle symptoms and functional outcomes at 6 months among older adults with an unstable ankle fracture.
The US Burden of Disease Collaborators used a systematic analysis of descriptive epidemiology of diseases and injuries, their sequelae, and risk factors or clusters of risk factors from 1990 to 2010 to describe the health status of the United States. In an editorial, Fineberg discusses the health of the US population.
This randomized clinical trial compares the effects of early vs delayed initiation of renal replacement therapy on 90-day all-cause mortality among critically ill patients with AKI.
This randomized clinical trial compares the effects of short-term high-dose perioperative atorvastatin vs placebo on acute kidney injury following cardiac surgery.
This review article assesses data on nonalcoholic fatty liver disease and highlights the importance of early identification of patients with nonalcoholic steatohepatitis, which may help improve patient outcomes through treatment intervention, including transplantation for those with decompensated cirrhosis.
Stanley and coauthors conducted a randomized clinical trial among 50 antiretroviral-treated men and women with human immunodefiency virus infection (HIV) and abdominal fat accumulation to investigate the effect of the growth hormone–releasing hormone analog tesamorelin on visceral adipose tissue and liver fat.