To investigate incidence of severe combined immunodeficiency, Kwan and coauthors performed a retrospective observational study including data for 3 030 083 infants from a range of newborn screening programs in 10 US states plus the Navajo Area Indian Health Service.
This randomized trial evaluates the safety and effectiveness of adding treatment with tumor-treating fields to maintenance temozolomide in patients with glioblastoma after chemoradiation.
This report summarizes the experience of 1 patient with needlestick exposure to the Ebola virus and postexposure vaccination with VSVΔG-ZEBOV.
Carvajal and coauthors conducted a randomized clinical trial to assess the efficacy of selumetinib, a selective, non–adenosine triphosphate competitive inhibitor of the mitogen-activated protein kinase kinase (MEK) enzymes MEK1 and MEK2, among 120 patients with metastatic uveal melanoma.
Omuro and DeAngelis review the clinical management of malignant gliomas, including genetic and environmental risk factors such as cell phones, diagnostic pitfalls, symptom management, specific antitumor therapy, and common complications.