Yawn and coauthors summarize a 2014 evidence-based report on the management of sickle cell disease. In an accompanying Editorial, DeBaun discusses the challenge of creating an evidence-based guideline for sickle cell disease.
A 71-year-old woman with recent fatigue and night sweats but no family history of blood disorders tested with an elevated hemoglobin level and a low-normal erythropoietin level. How do you interpret the test results?
A 75-year-old woman with rheumatoid arthritis and genital herpes simplex virus 2 presented with painful, pruritic plaques on her buttock. She denied recent trauma to the area, skin exposures, fever, or lymphadenopathy. She takes prednisone, pregabalin, and valacyclovir. What would you do next?
A 32-year-old woman with severe headaches had normal laboratory and neurologic results except for an elevated platelet count. What is the most likely cause for the elevated platelet count?
A 67-year-old woman presented with fatigue for 4 weeks; a history of type 2 diabetes mellitus, hypertension, hyperlipidemia, and allergic rhinitis; and leukocytosis with predominant granulocytes. What’s the diagnosis?