Showing 1 – 20 of 2025
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  • Reversing Drug-Induced Paralysis

    Abstract Full Text
    JAMA. 2016; 315(5):456-456. doi: 10.1001/jama.2015.19422
  • Implantable Spinal Cord Stimulator Allows Voluntary Movement in Individuals With Lower-Extremity Paralysis

    Abstract Full Text
    JAMA. 2014; 312(2):120-120. doi: 10.1001/jama.2014.7508
  • Overcoming Paralysis

    Abstract Full Text
    JAMA. 2008; 300(21):2476-2476. doi: 10.1001/jama.2008.739
  • The Importance of Biodiversity to Medicine

    Abstract Full Text
    JAMA. 2008; 300(19):2297-2299. doi: 10.1001/jama.2008.655
  • Paralysis Research Legislation

    Abstract Full Text
    JAMA. 2005; 293(2):151-151. doi: 10.1001/jama.293.2.151-c
  • Harnessing Brain Signals Shows Promise for Helping Patients With Paralysis

    Abstract Full Text
    JAMA. 2004; 291(18):2179-2181. doi: 10.1001/jama.291.18.2179
  • As West Nile Virus Season Heats Up, Blood Safety Testing Lags Behind

    Abstract Full Text
    JAMA. 2003; 289(18):2341-2342. doi: 10.1001/jama.289.18.2341
  • Preventing Paralysis

    Abstract Full Text
    JAMA. 1999; 282(8):723-723. doi: 10.1001/jama.282.8.723-JQU90006-4-1
  • JAMA

    Figure: Implantable Spinal Cord Stimulator Allows Voluntary Movement in Individuals With Lower-Extremity Paralysis

    Kent Stephenson, the second patient with complete lower-extremity paralysis to undergo epidural stimulation of the spinal cord, voluntarily raises his leg while receiving epidural stimulation at the University of Louisville’s Kentucky Spinal Cord Injury Research Center in Louisville.
  • JAMA

    Figure: Spinal Cord Injury Research Shows Promise

    David Renaud, a research subject in the Miami Project to Cure Paralysis, walks using functional electrical stimulation. Renaud, a paraplegic since 1994, uses the system for the physical and psychological benefits it provides. (Photo credit: Miami Project to Cure Paralysis)
  • JAMA

    Figure 2. Neuromuscular Scores in Each Limb Segment in Patients With Intensive Care Unit–Acquired Paresis (ICUAP)

    Mean Medical Research Council scores for each limb segment in the 24 ICUAP patients. The Medical Research Council score attributes a value between 0 (complete paralysis) and 5 (normal muscle strength) to each limb segment. Error bars represent SDs.
  • JAMA

    Figure: Example of Relationship of Risk Factors With Lifetime Benefit of Colorectal Cancer Screening With Colonoscopy

    CRC indicates colorectal cancer; RR, relative risk.aIndividuals are classified as having moderate comorbidity if diagnosed with an ulcer, rheumatologic disease, peripheral vascular disease, diabetes, paralysis, or cerebrovascular disease and in case of a history of acute myocardial infarction; as having severe comorbidity if diagnosed with chronic obstructive pulmonary disease, congestive heart failure, moderate or severe liver disease, chronic renal failure, dementia, cirrhosis and chronic hepatitis, or AIDS; and as having no comorbidity if none of these conditions is present.bThe range of the background risk for CRC is based on the National Cancer Institute’s Colorectal Cancer Risk Assessment Tool. In white women, the minimum background risk for CRC is 0.5, the maximum background risk in the absence of a family history of CRC is 1.8, and the maximum risk in the presence of a family history of CRC is 3.5.
  • JAMA

    Figure: Sagittal and Axial Magnetic Resonance Imaging (MRI) of the Spinal Cord From Representative Patients in This Case Series

    Spinal cord MRI typically revealed longitudinally extensive (>3 vertebral bodies) T2 hyperintense lesions affecting spinal gray matter with relative sparing of adjacent white matter (A-J), although various accompanying radiological features were also observed. In some patients, lesions traversed the entire cord with a stable, symmetric appearance (arrowhead in A), whereas other patients demonstrated patchy, asymmetric lesions affecting discrete segments of the cord (arrowheads in B and C). In other patients, subtler lesions (white arrowhead in D) were observed adjacent to more severely affected segments manifesting cord edema (black arrowhead in D). Brainstem lesions were occasionally observed (white arrowheads in C and D) and often correlated with cranial nerve weakness. Although certain lesions appeared to affect dorsal as well as ventral gray matter, the lesions were typically more prominent within the ventral gray matter (G and J), consistent with the location of the spinal motor neurons. Axial sequences revealed spinal lesions that included a “snake eyes” or “owl eyes” appearance highlighting the bilateral ventral horns (F and J), increased T2 signal highlighting the majority of the spinal gray matter (G), unilateral lesions of the ventral horns (H and I), lesions affecting both spinal gray matter and adjacent white matter (I). A distended bladder was observed (white arrowhead in part E) in association with edematous lesions of the conus (black arrowhead in E) in a child with lower limb paralysis. Brainstem and cord lesions are consistent with descriptions of similar cases reported in Colorado in 2014. The black arrowheads in the sagittal images (A-E) demarcate the approximate anatomic level of the associated axial images (F-J, respectively).
  • Antiviral Agents Added to Corticosteroids for Early Treatment of Adults With Acute Idiopathic Facial Nerve Paralysis (Bell Palsy)

    Abstract Full Text
    JAMA. 2016; 316(8):874-875. doi: 10.1001/jama.2016.10160

    This Clinical Evidence Synopsis summarizes a Cochrane review of clinical trials comparing the effects of antiviral therapies plus oral corticosteroids vs oral corticosteroids alone for patients presenting within 72 hours of onset of Bell palsy.

  • The Epidemic of Infantile Paralysis

    Abstract Full Text
    JAMA. 2016; 316(1):107-107. doi: 10.1001/jama.2015.17092
  • Advances in Surgical Treatment of Facial Nerve Paralysis in ChildrenFacial Nerve Paralysis in Children

    Abstract Full Text
    JAMA. 2011; 305(20):2106-2107. doi: 10.1001/jama.2011.689
  • Acute Flaccid Myelitis of Unknown Etiology in California, 2012-2015

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    JAMA. 2015; 314(24):2663-2671. doi: 10.1001/jama.2015.17275

    This case series describes the clinical characteristics and natural course of patients with acute flaccid paralysis reported to the California Department of Public Health between June 2012 and July 2015, and compares case incidence during a US enterovirus D68 outbreak with other monitoring periods.

  • Management of Graves Disease: A Review

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    JAMA. 2015; 314(23) doi: 10.1001/jama.2015.16535

    This review summarizes use of antithyroid drugs, radioactive iodine, or thyroidectomy in treating Graves disease.

  • Cluster of Tick Paralysis Cases—Colorado, 2006

    Abstract Full Text
    JAMA. 2006; 296(14):1721-1722. doi: 10.1001/jama.296.14.1721
  • West Nile Virus: Review of the Literature

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    JAMA. 2013; 310(3):308-315. doi: 10.1001/jama.2013.8042

    Petersen and coauthors reviewed the ecology, virology, epidemiology, clinical characteristics, diagnosis, prevention, and control of West Nile virus after searching the PubMed electronic database through February 5, 2013. In an Editorial, Ostroff urges maintenance of vector surveillance and control programs.