This randomized clinical trial compares the effects of micafungin vs placebo on 28-day fungal infection–free survival among nonneutropenic critically ill patients with ICU-acquired sepsis, Candida species colonization at multiple sites, and multiple organ failure.
This prospective study sought to determine the incidence, risk factors, and attributable mortality of ICU-acquired infections in patients admitted with or without sepsis.
This cohort study uses health system and research cohort data to compare the ability of existing vs new clinical criteria for sepsis to identify intensive care unit patients with suspected infection at higher mortality risk.
This article presents updated definitions of and clinical criteria for diagnosing sepsis and septic shock based on recommendations from an expert task force.
This article describes the results of a meta-analysis of criteria used to identify adults with septic shock and the processes by which a critical care task force used the results to revise current septic shock definitions.
This Medical News & Perspectives article discusses new sepsis diagnostic guidelines developed by a joint task force of the Society of Critical Care Medicine and European Society of Intensive Care Medicine.
This review summarizes evidence on the clinical management of Staphylococcus aureus bacteremia and offers treatment recommendations for specialists and generalists.