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June 1921

THE SEROLOGY OF THE SPINAL FLUID AND BLOOD IN EPIDEMIC ENCEPHALITIS

Arch NeurPsych. 1921;5(6):710-722. doi:10.1001/archneurpsyc.1921.02180300075006
Abstract

The subject matter which we present has, for the sake of clearness, been divided into three parts; the first contains a review of the literature, the second, data based on the 245 case reports obtained from the foregoing sources, and the third, a section devoted to differential diagnosis by means of the blood and spinal fluid serology.

REVIEW OF THE LITERATURE  Until the publication, in 1917, of the description of the first cases of epidemic encephalitis in Vienna, no reliable statistics of the changes in the blood and spinal fluid in this disease are obtainable. At this time, von Economo1 gave an account of the clinical and laboratory findings which we shall consider the first accurate data on the subject. He pointed out the following changes in the spinal fluid: An excess of globulin was found and the spinal fluid cell counts ranged from normal to 43. The fluid

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