As the cerebrospinal fluids of several patients in the Michael Reese Hospital who had epidemic encephalitis at about the same time showed similar gold chlorid curves—a change to violet in the syphilitic zone—it seemed advisable to look up the spinal fluid findings of other patients with this disease who had been in the hospital. It appeared important also to attempt to correlate the colloidal gold chlorid curves in the entire series with the other changes in the fluids, to determine whether the laboratory examination of the spinal fluid in this disease might yield any findings which, considered in relation to each other, would be of diagnostic aid.
The colloidal gold chlorid solutions used in the tests conformed with the usual requirements, that is: 1. The fluids were deep red, clear to both direct and transmitted light. 2. They were neutral to 1 per cent, solution of alizarin red in
HOWELL KM. THE COLLOIDAL GOLD CHLORID CURVE IN EPIDEMIC ENCEPHALITIS. Arch NeurPsych. 1922;7(2):229-234. doi:10.1001/archneurpsyc.1922.02190080078008