To Dandy, we owe the brilliant conception of injecting air into the ventricles, studying them with the roentgen ray and localizing intracranial lesions from the defects in the ventricular outline. While his results with the procedure have been impressive, in other hands the exact value of the intraventricular injection of air for the localization of new growths within the brain is somewhat uncertain. Although the series of cases is relatively small, nevertheless I feel that the results in some measure confirm his claims.
Forty-four ventriculograms of forty patients were made. In fifteen cases the ventriculogram findings were confirmed at operation or necropsy. In nine cases, the exposure of the suspected area failed to reveal the disease, although, from the neurologic examination and subsequent course of the case, I believe that the lesion existed in the region exposed. Of these nine tumor suspects, unverified, in six the ventriculogram placed the lesion
GRANT FC. THE VALUE OF VENTRICULOGRAPHYA CLINICAL EXPERIENCE BASED ON A SERIES OF FORTY CASES. Arch NeurPsych. 1923;10(2):154-166. doi:10.1001/archneurpsyc.1923.02190260015002