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January 1924

FAMILIAL MUSCULAR DYSTROPHYSTUDIES OF SIX CASES IN ONE FAMILY

Author Affiliations

PHOENIX, ARIZ.; NEW YORK

Arch NeurPsych. 1924;11(1):43-53. doi:10.1001/archneurpsyc.1924.02190310049003
Abstract

The literature concerning muscular dystrophy abounds in instances of familial involvement. We have found no clinical report of so heavy an incidence in one family as we here report; seven cases of muscular dystrophy (one dead) have occurred among twelve children born to the same parents. Poore1 reviewed eighty-five cases among which there are thirty-seven instances of two or more in the same family. Among the 220 instances cited by Gowers,2 118 occurred in thirty-nine families. Among the cases cited by Erb,3 56 per cent, showed familial aspects. In the study of Collins and Climenko,4 fifty cases are reviewed, twenty of which show hereditary aspects. Eshner5 has cited twenty cases at the Orthopedic Hospital in Philadelphia, in two instances similar disorders being found in other members of the family. Among the nine cases studied by Janney, Goodhart and Isaacson6 at the Montefiore Home, there

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