Although reports of the occurrence of Friedreich's ataxia in siblings are not uncommon, rarely has an opportunity been presented for the clinical study during the different stages of the disease and of the spinal cord lesions in such cases. The cases here described were those of two brothers, fullblooded negroes, each of whom was 8 years of age when the symptoms were first observed. The duration of life, from the time of the onset of the illness, was three years in the case of one brother, and seven years in the case of the other.
The case of the elder brother was described by Lloyd and Newcomer,1 in 1921. At that time the younger brother was still alive. His death, in October, 1924, furnished the opportunity for the present comparison of the two cases.
REPORT OF CASES
Case 1.—Family History.
—The parents were living and in good health. There
BARRETT TM. FRIEDREICH'S ATAXIACLINICAL AND POSTMORTEM STUDY OF TWO CASES IN BROTHERS AT DIFFERENT STAGES OF THE DISEASE. Arch NeurPsych. 1927;17(1):28-43. doi:10.1001/archneurpsyc.1927.02200310031004