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November 1927

Clinical and Occasional Notes:A CASE OF MULTIPLE SCLEROSIS COMPLICATED BY CANCEROUS METASTASES TO THE SPINE

Author Affiliations

New York

From the service of Prof. Georges Guillain, laboratory of Dr. Ivan Bertrand, Hospice de la Salpêtrière, Paris.

Arch NeurPsych. 1927;18(5):789-791. doi:10.1001/archneurpsyc.1927.02210050121009
Abstract

REPORT OF CASE 

History.  —V. B., aged 48, a dressmaker, when first seen in the outpatient department of the Salpêtrière, May 17, 1924, complained of difficulty in walking, shocks in the lower extremities, and numbness and tingling of the right hand. Except that she had been treated for a long time for anemia, and had had two miscarriages, the past history was without importance; there was no history of infectious disease. The family history was unimportant.The onset was gradual, and occurred at least eight years before examination, with shocks in the legs that varied from time to time. Four years later, the shocks increased and were supplemented by sensations of heaviness with difficulty in walking. After further remissions and relapses, the patient had been unable for a year to go about without assistance; she complained of great rigidity of the legs, especially after resting for some time, and of

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