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It is deplorable that the author did not follow the example of his distinguished countryman, August Wimmer, who wrote his excellent monograph on chronic epidemic encephalitis in English. Fortunately, the main facts stated in Winther's monograph are given in an article written in French (Acta psychiat. et neurol. 3:165, 1928). He finds that involvement of the optic nerve is more frequent than is generally supposed, as he has collected 150 cases from the literature and has observed thirty-two cases personally. Eight of these cases were verified by necropsy. Naturally, a wrong diagnosis of brain tumor frequently has been made, leading to exploratory operations. Papilledema in encephalitis is prone to appear suddenly and to disappear spontaneously or after repeated lumbar puncture. It sometimes leads to blindness. Most frequently the cause is increased intracranial pressure. In a very few cases it is due to local mechanical conditions such as chronic meningitis
Encephalitis Epidemica med Optikusforandringer.. Arch NeurPsych. 1929;21(4):987-988. doi:10.1001/archneurpsyc.1929.02210220258017