Clinical neurology has contributed little to the knowledge of the corpus callosum. Embryologic, anatomic and pathologic studies have elucidated many doubtful points in the knowledge of this portion of the brain, but knowledge of the clinical symptoms produced by lesions of the corpus callosum is extremely fragmentary and uncertain. Syndromes have been described which purport to be characteristic of lesions in this region. These, however, fail to elucidate features that are peculiar to involvement of the callosum as distinct from other portions of the brain.
Recent experience with a case in which we were able to diagnose a tumor springing from the corpus callosum stimulated us to review our cases of this type in order to determine whether a syndrome could be defined which seemed clearly to indicate involvement of the callosal region.
REPORT OF CASES
Our first case is of interest because we were able clinically to diagnose an
ALPERS BJ, GRANT FC. THE CLINICAL SYNDROME OF THE CORPUS CALLOSUM. Arch NeurPsych. 1931;25(1):67-86. doi:10.1001/archneurpsyc.1931.02230010079004