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November 1931

SPINAL CORD CHANGES IN LYMPHOGRANULOMATOSIS

Author Affiliations

CHICAGO

From the Institute of Neurology, Northwestern University Medical School.

Arch NeurPsych. 1931;26(5):1009-1026. doi:10.1001/archneurpsyc.1931.02230110107005
Abstract

The present investigation is based on reports of forty-three cases of Hodgkin's disease published in the literature, in which a clinical history is given, with observations made at autopsy or operation. Three cases which had personally been studied were added. The purpose of this study was, first, to obtain statistical data on the histopathologic changes of the spinal cord in lymphogranulomatosis from a verified material which is relatively large as compared with the rare involvement of the spinal cord in this disease. Second, the effect of x-ray treatment on the granulomatous masses invading the spinal canal was to be studied, with preference for those cases in which they had previously been verified by laminectomy.

As to the frequency of involvement of the spinal cord in Hodgkin's disease, it may be quoted from Ginsburg,1 part of whose material was at my disposal at the autopsy, that from 1914 to 1925,

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