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December 1931

SUBACUTE COMBINED DEGENERATION OF THE CORDCHANGES FOLLOWING LIVER THERAPY; A HISTOPATHOLOGIC STUDY

Author Affiliations

NEW YORK

From the Neuropathological Laboratory, Montefiore Hospital.

Arch NeurPsych. 1931;26(6):1195-1219. doi:10.1001/archneurpsyc.1931.02230120078004
Abstract

TABLE OF CONTENTS 

  • Introduction

  • Material Used and Method of Procedure

  • Report of Cases

    1. Cases of Subacute Combined Degeneration in which the Patients Did Not Receive Liver Therapy (Table 1)

    2. Cases of Subacute Combined Degeneration in which the Patients Received Liver Therapy (Table 2)

  • Comment

  • Summary and Conclusions

It is recognized that, clinically, liver therapy produces a beneficial effect in pernicious anemia. The effect of this form of treatment on the spinal cord in subacute combined degeneration is a moot question. The purpose of this study is to determine what influence, if any, liver therapy has on the myelin sheaths, axis cylinders and glial tissue in cases of pernicious anemia presenting neurologic signs and symptoms. An attempt will be made to demonstrate that liver therapy does not cause regeneration of the axis cylinders in the spinal cord and that the only change noted was a glial overgrowth of varying intensity.In

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