In a previous paper1 we expressed the view that the progressive changes developing in persons with epilepsy in the course of time have a definite symptomatology and evolution which can be described in neurologic terms. We called these progressive neurologic changes "neurosomatic deterioration." Derived solely from clinical observations, this view was a purely clinical concept; it was natural, therefore, that we looked for an opportunity to study the pathologic changes that might underlie the symptomatology of deterioration.
Two cases have come to autopsy, and as both of them had fairly complete case histories these brains were submitted to microscopic study.
REPORT OF CASES
—Irven G., a boy, aged 12, was admitted to the Monson State Hospital because of epilepsy and advanced mental and physical deterioration. The family history was negative as to epilepsy, nervous or mental disease, alcoholism and syphilis. Both parents are living and in
HODSKINS MB, YAKOVLEV PI. NEUROSOMATIC DETERIORATION IN EPILEPSYA CLINICOPATHOLOGIC CONTRIBUTION TO THE CONCEPT WITH A REPORT OF TWO CASES. Arch NeurPsych. 1932;27(1):113-137. doi:10.1001/archneurpsyc.1932.02230130119007