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April 1933

PALATAL MYOCLONUSREPORT OF TWO CASES WITH NECROPSY

Author Affiliations

WASHINGTON, D. C.

From St. Elizabeth's Hospital.

Arch NeurPsych. 1933;29(4):742-755. doi:10.1001/archneurpsyc.1933.02240100061005
Abstract

Continuous rhythmic myoclonic movements of the palate and pharynx have evoked considerable interest recently in France under the stimulus of Foix,1 and his pupils have continued the work so lamentably cut short, as witnessed by the thesis of Gallet2 and the careful anatomic investigations of van Bogaert. Leshin and Stone's3 recent report covers particularly the German and the English literature, but contains only six cases in which necropsy was performed. Foix believed that he had found the specific lesion underlying the condition, namely, destruction of the central tegmental fasciculus in the pons, but the studies of Klien4 and more recently of van Bogaert and Bertrand5 have thrown some doubt on the constancy of this lesion. These authors and others have incriminated the dentate nucleus of the cerebellum. In both conditions, however, there is an accompanying hypertrophic degeneration of the inferior olive, a lesion that has

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