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May 1933

ENCEPHALOPATHIA ALCOHOLICA(POLIOENCEPHALITIS HÆMORRHAGICA SUPERIOR OF WERNICKE)

Author Affiliations

NEW YORK

From the Research Department of the Psychopathic Division of Bellevue Hospital.

Arch NeurPsych. 1933;29(5):990-1053. doi:10.1001/archneurpsyc.1933.02240110058002
Abstract

Acute and chronic alcoholic intoxications produce a variety of clinical pictures which are fairly well differentiated from each other. This paper will deal principally with the so-called polioencephalitis haemorrhagica of Wernicke. This condition may be associated with polyneuritis, and there are many associated but atypical pictures, at least if one considers Wernicke's classic description. More recent investigations, especially those of Gamper,1 Ohkuma2 and Neubuerger3 disclosed the relation of polioencephalitis to other alcoholic psychoses. In the classic picture of polioencephalitis the following characteristics have been emphasized; ocular palsies, deep clouding of consciousness, asynergia and toxic changes. Alcohol has been shown to be important in the etiology, but Oppenheim4 and Neuberger3 have found that influenza and other conditions may produce the same picture. Small hemorrhages in the ventricular gray areas and around the oculomotor nuclei were found long ago in cases of chronic alcoholism by Raimon.5

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