The procedure of arterial encephalography has encountered certain difficulties in its general adoption. Operators have feared to puncture the carotid and above all to inject sodium iodide to obtain opacity of the arteries. In my book I1 record the studies carried out in connection with arterial encephalography, and I analyze the accidents attendant on the procedure. To quote from this publication:
From our first cerebral arteriography by the injection of 25 per cent sodium iodide into the internal carotid (June, 1927) to the present time, we have had a few complications. In short, we have observed, following the intracarotid injection, occasional hemiplegia, which has disappeared three or four days later. More frequently, we have seen short epileptic seizures which have become more rare and, above all, less forceful since the adoption of the administration of phenobarbital.
But this aspect of the problem raises doubt and prejudice in the minds
MONIZ E. CEREBRAL ANGIOGRAPHY WITH THOROTRAST. Arch NeurPsych. 1933;29(6):1318-1323. doi:10.1001/archneurpsyc.1933.02240120141013