Since Marie's1 famous article on acromegaly appeared in 1886, many clinical syndromes have been ascribed to disorders of the pituitary body. Later it was shown that some of these syndromes might be produced by lesions of the hypothalamus. The exact rôles of these two structures in the production of the so-called pituitary syndromes are not yet generally agreed on. For this reason it has seemed worth while to record a case of sexual infantilism without dwarfism caused by a glioma of the hypothalamic region.
REPORT OF A CASE
—The patient, a man, aged 22, first came to the clinic on Jan. 28, 1931, complaining of failing vision. Examination disclosed bilateral papilledema, and he was admitted to the hospital on the same day. Six months before admission, while chopping wood, he had suddenly felt faint and dizzy. He took a drink of water, promptly vomited and experienced an excruciating
Hamby WB. SPONGIOBLASTOMA BIPOLARE IN THE REGION OF THE HYPOTHALAMUSAssociated With Infantilism and Without Dwarfism. Arch NeurPsych. 1934;31(6):1258-1265. doi:10.1001/archneurpsyc.1934.02250060144010