In recent years attention has been drawn to a strange picture in the roentgenograms in some cases of suspected angioma of the brain, especially in cases associated with epilepsy. The diagnosis of angioma of the brain has been made in these cases because of the presence of an angioma of the skin of the face. None of the patients has died, so that no autopsy has hitherto been performed.
In 1921, Ove Wissing demonstrated before the Radiological Society of Copenhagen a roentgenogram of the skull of a young man which showed an unusual shadow. This shadow, which was localized in the right occipital lobe, had a sinuous form corresponding to the outline of the pia mater. Consequently, it was considered to be a calcification of the pia mater. This report was not published, as the Radiological Society of Copenhagen had then only recently been established.
The first published case was
KRABBE KH. FACIAL AND MENINGEAL ANGIOMATOSIS ASSOCIATED WITH CALCIFICATIONS OF THE BRAIN CORTEXA CLINICAL AND ANATOMOPATHOLOGIC CONTRIBUTION. Arch NeurPsych. 1934;32(4):737-755. doi:10.1001/archneurpsyc.1934.02250100059005