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This is a short monograph on the modern treatment of dementia paralytica. The authors call attention to the inefficacy of the usual antisyphilitic therapy (mercury, bismuth and the arsphenamines). They give their results with the use of the sodium salt of acetarsone (acetylaminohydroxy-phenylarsonic acid) and compare these results with the results of malaria therapy as recorded in the literature.
The authors divide the hundred and twenty-five cases in which acetarsone therapy was administered into three groups: the expansive cases (thirty-one), those in which there was slight mental deterioration (forty-one) and those in which there was dementia (fifty-three). In the expansive group they obtained good results in 68 and poor results in 32 per cent; in the mildly demented group, good results in 58.5 and poor results in 41.5 per cent, and in the demented group, good results in 26.4 and poor results in 73.6 per cent. The serologic results with
Les traitements modernes de la paralysie générale.. Arch NeurPsych. 1934;32(4):913-914. doi:10.1001/archneurpsyc.1934.02250100235022