In connection with a theory of the cause of epilepsy held by one of us (B. W. McK.) to be published later, it was of interest to investigate the proteins of the blood serum of patients having this disease. Intensive studies have been made of the blood in cases of epilepsy,1 but no significant changes from the normal have been found. However, not much attention has been given to the serum proteins, in spite of their importance in influencing the water balance between the blood and the tissues and other possible functions not yet well understood. The few observations which have been made on serum proteins are not conclusive and seem to leave the field open for further work.
Meyer and Brühl,2 Brühl3 and Meyer4 measured the albumin content of the serum in a group of sixteen patients, using the refractometric and Kjeldahl methods. They found
McKENZIE BW, McCHESNEY EW. PROTEINS OF THE BLOOD SERUM IN CASES OF ESSENTIAL EPILEPSY. Arch NeurPsych. 1935;34(4):764-767. doi:10.1001/archneurpsyc.1935.02250220068006