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June 1936

OXYGEN SATURATION OF THE ARTERIAL BLOOD IN EPILEPSY

Author Affiliations

BOSTON

From the Department of Neurology, Harvard Medical School, and the Neurological Unit, Boston City Hospital. This paper is no. XIX in a series entitled "Studies in Epilepsy." Assistance in this research was received from the Harvard Epilepsy Commission.

Arch NeurPsych. 1936;35(6):1198-1202. doi:10.1001/archneurpsyc.1936.02260060040002
Abstract

Because nerve tissue, more than any other tissue of the body, is dependent on oxygen for its proper functioning and because it has been shown1 that seizures may be precipitated in patients who have frequent attacks of petit mal by the breathing of air deficient in oxygen, the question of whether blood going to the brain of persons with epilepsy has a normal oxygen tension is a pertinent one. So far as we are aware, no attempt has been made to shed light on this question.

MATERIALS AND METHODS  The patients examined were under treatment for epilepsy and were private or hospital patients. No division of the patients on the basis of etiology was attempted. The hearts and lungs of all were found to be normal by routine methods of examination. In every instance blood was taken with the patient recumbent after a ten minute or longer period of

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