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October 1938

STUDIES ON THE HUMAN NEUROMUSCULAR MECHANISMII. EFFECT OF VENTROMEDIAL CHORDOTOMY ON MUSCULAR SPASTICITY IN MAN

Author Affiliations

CHICAGO

From the Division of Neurology and Neurosurgery, the University of Chicago.

Arch NeurPsych. 1938;40(4):639-662. doi:10.1001/archneurpsyc.1938.02270100011001
Abstract

Decerebrate rigidity in the cat has much in common with the spastic paralysis which results from cerebral lesions in man. It is thus natural that an endeavor should be made to confirm the findings in the lower animal by appropriate investigations in man and that attempts should be made to convert the results of experiments in the laboratory into therapeutic procedures of value in the clinic. The present paper is the report of such an attempt.

It has long been known that appropriate transection of the brain stem gives rise to the condition known as decerebrate rigidity, a condition characterized by extensor rigidity and enhancement of the stretch reflex and the tendon reflexes, e. g., the knee jerk, as well as other alterations in the reflex activities of the skeletal muscles. Although such transections are, for the sake of convenience, usually made through the mesencephalon in the region of the

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