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In this monograph the author has collected material from both clinical and experimental literature which indicates that lesions in descending cervical sympathetic pathways cause a typical Homer's syndrome on the side of the lesion. These interruptions may occur in the peripheral sympathetic chain, the spinal cord, the brain stem or the hypothalamus, or even in the thalamus. To investigate the last, which heretofore has been seen only in clinical cases, the author placed electrolytic lesions in the diencephalon of dogs. Thirty-one operations were performed, and 3 are reported on. In 2 dogs a typical Horner's syndrome, with miosis, exophthalmos and narrowing of the palpebral fissure, was transiently obtained. The lesions were in the anterior and superior part of the thalamus. In the third animal, with a lesion in the external thalamic nucleus, only homolateral miosis was obtained. The author used the reactions of the pupil to cocaine and atropine to
Les inégalités pupillaires d'origine sympathique dans les lésions du système nerveux central.. Arch NeurPsych. 1939;41(1):222. doi:10.1001/archneurpsyc.1939.02270130232015