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This collective volume contains 21 contributions by members of the department of neurology of the First State Medical Institute of Moscow to various problems of epilepsy—clinical, physiologic and chemical. Fourteen articles deal with metabolism of epilepsy and comprise a variety of chemical studies of the blood, spinal fluid and urine—before, during and after the epileptic attacks. Each problem is taken up in detail, in a separate chapter, accompanied by numerous tables. The chapters deal exhaustively with such problems as metabolism of epilepsy in general; total protein content of the urine of epileptic persons; proteids of the blood, and cholesterol content, general condition and inorganic and organic constituents of the blood. In addition, there are chapters on the hemoencephalic barrier, muscle tone in epilepsy, the epileptic process in general and the psychologic peculiarities of epileptic persons. As to the possible explanation of the epileptic attack, Sepp considers Gowers' hypothesis—that of a
Epilepsy: Fundamental Problems of Its Pathogenesis.. Arch NeurPsych. 1939;41(5):1085. doi:10.1001/archneurpsyc.1939.02270170223017