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Examinations were made of the spinal fluid and blood of all new patients admitted to the men's division at Central State Hospital, Indianapolis, during 1932 and 1933. Examination of the spinal fluid included: Ross and Pandy tests; cell counts; the colloidal gold test, and the Wassermann, Kahn and Kline tests.
In 1932, 28 (22.3 per cent) of 125 psychotic patients admitted had typical clinical dementia praecox. Of these, 32 per cent gave positive serologic reactions as tabulated.
In 1933, 35 (22.3 per cent) of 156 psychotic patients admitted had dementia praecox. Of these, 28.5 per cent gave positive serologic reactions, as shown in the following tabulation.
Of the 1932 group of patients with dementia praecox, 19 (68 per cent) gave completely normal serologic reactions. Six of these 19 patients were discharged as improved or recovered, but the remaining 13 did not improve sufficiently to be furloughed. Similarly, in the 1933
Sharp WL. SEROLOGIC REACTIONS IN SCHIZOPHRENIAPrognostic Value. Arch NeurPsych. 1939;41(6):1229-1230. doi:10.1001/archneurpsyc.1939.02270180157014