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July 1939

VASCULAR PATTERN OF CERTAIN INTRACRANIAL NEOPLASMSSTUDIES WITH THE BENZIDINE STAIN

Author Affiliations

IOWA CITY; BOSTON

From the Neurological Unit of the Boston City Hospital and the Department of Neurology, Harvard Medical School.

Arch NeurPsych. 1939;42(1):44-66. doi:10.1001/archneurpsyc.1939.02270190052003
Abstract

This study was conducted for the purpose of determining the vascular pattern of a group of tumors of the brain. Numerous pathologic reports and classifications of intracranial neoplasms appear in the literature, with an occasional investigator devoting particular attention to the vascular arrangement. Elsberg and Hare1 determined the number and situation of vessels in tumors of the brain as seen in ordinary stained specimens. Special stains, such as the Perdrau ammoniacal silver method for the study of reticulin around blood vessels, have been used.2 Articles have been devoted to the special study of changes in the blood vessels of gliomas, particularly spongioblastoma multiforme.3 Campbell, Alexander and Putnam4 applied the technic of the benzidine stain to the study of the vascular pattern of a meningioma, while Alexander and Putnam5 later demonstrated the pattern of an oligodendroglioma and a protoplasmic astrocytoma.

MATERIAL AND METHODS  Most of the

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