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September 1939

AN UNUSUAL FORM OF LYMPHOCYTIC CHORIOMENINGITIS

Author Affiliations

Minneapolis

From the Division of Nervous and Mental Diseases, University of Minnesota Medical School.

Arch NeurPsych. 1939;42(3):507-512. doi:10.1001/archneurpsyc.1939.02270210145007
Abstract

Lymphocytic meningitis was originally described as an acute, self-limited, benign inflammation of the meninges. However, since the original presentation of this condition as a primary clinical syndrome by Wallgren,1 in 1925, several interesting case reports have appeared in the literature which indicate that this may not always be an innocuous disease.

The condition in Wallgren's cases was characterized by an acute onset, and the symptoms usually consisted of nausea, vomiting, slight elevation of temperature and evidences of meningeal irritation. The disease had a benign course, lasting about ten days. Recovery was complete, and there were no sequelae. Since the original account by Wallgren, the same syndrome has been described by numerous investigators. The clinical features of the illness have come to be well recognized, and, in addition, a virus has been isolated within the past few years which is considered to be the etiologic agent in at least one

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