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November 1939

A CLASSROOM OUTLINE FOR THE PATHOLOGIC DIAGNOSIS OF PRIMARY INTRACRANIAL NEOPLASMSSix Differential Characteristics

Author Affiliations

Boston

From the Neurological Unit, Boston City Hospital, and the Department of Neurology, Harvard Medical School.

Arch NeurPsych. 1939;42(5):912-914. doi:10.1001/archneurpsyc.1939.02270230134011
Abstract

The classification of intracranial neoplasms, since Bailey and Cushing's1 monumental work, is based on the histogenetic principle. The scientific and practical validity of this principle is beyond doubt, but the student when confronted with the problem of making a pathologic diagnosis does not find it easy to think consistently in terms of histogenesis and by his attempt to do so may be distracted from the picture as a whole. Furthermore, the histogenetic origin of a given tumor is, in routine laboratory work, not always easy to ascertain, and in some cases, for instance in that of the neurinoma, has remained controversial, some authors considering the schwannian cells as ectodermal in origin, others as mesodermal and others classifying them as ectomesoderm (Held2). Therefore it has seemed advisable, in order to standardize descriptions especially for teaching purposes, to prepare an outline for classification of tumors of the brain based on

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