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February 1940

CHANGES IN THE ELECTROENCEPHALOGRAM DURING METRAZOL THERAPY

Author Affiliations

BOSTON; WAVERLEY, MASS.

From the Department of Physiology of the Harvard Medical School, and the McLean Hospital, Waverley, Mass.

Arch NeurPsych. 1940;43(2):341-355. doi:10.1001/archneurpsyc.1940.02280020149013
Abstract

We have recorded the electroencephalogram of a patient under treatment for schizophrenia, beginning before each injection of metrazol and continuing without interruption for from two to three hours. The patient was given 24 metrazol treatments. Reactions during 22 of his treatments were so recorded, and several subsequent studies were made for a year after termination of the treatment.

REPORT OF A CASE 

History.  —The patient was a man aged 33, the second oldest of five siblings, four living and one dead, in a family with no known history of mental disorder. There was no information concerning his birth. He was obese at the age of 10, but later became slender, with a tendency to be underweight. He had influenza in 1918. He took prizes for scholarship in high school, spent two years in graduate work and was one of a few students chosen to study in Europe in 1929. He

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