This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
This monograph presents the results of a series of experiments concerning cerebral embolism with small particles, observed by means of the Forbes window technic. Powdered glass wool was used as an embolic agent in most of the experiments, and the particles were of a size to obstruct arterioles, or larger. Other mineral particles, and in one series of experiments gaseous emboli, were employed. The pial circulation was studied in some animals during the injection of particles, in others at intervals up to several months afterward.
Embolism with small particles demonstrates clearly the anastomosis of arteries in the pia. In many experiments no parenchymal lesions were produced. The collateral blood vessels around an obstruction dilated, and the region became cyanotic. Further, this method of study showed that local vasoconstriction is readily produced by the mechanical irritation of solid emboli. (The authors were aware that the mineral particles which they employed are
Les embolies cérébrales.. Arch NeurPsych. 1940;43(3):614. doi:10.1001/archneurpsyc.1940.02280030188020