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October 1940

CHANGES IN THE NERVOUS SYSTEM FOLLOWING CARBON DISULFIDE POISONING IN ANIMALS AND IN MAN

Author Affiliations

PHILADELPHIA

From the Department of Neurology, Jefferson Medical College of Philadelphia, and the Laboratory of Neurosurgery, Hospital of the University of Pennsylvania.

Arch NeurPsych. 1940;44(4):725-739. doi:10.1001/archneurpsyc.1940.02280100027003
Abstract

The problem of carbon disulfide poisoning has become increasingly important in recent years, owing to extensive use of this chemical in the rayon industry. Cases of poisoning due to exposure to carbon disulfide are reported from time to time, and the problem not infrequently arises whether the clinical and pathologic changes noted in a given case are in fact the result of carbon disulfide poisoning. For this reason an attempt has been made to gather all available data concerning the changes in the nervous system in carbon disulfide poisoning both in man and in the experimental animal, in order to determine whether there are specific alterations which result from this poisoning. In this paper the lesions of the nervous system in 9 dogs which were intoxicated with the chemical are reported and compared with the changes observed in cases of carbon disulfide poisoning in man.

REVIEW OF LITERATURE 

Carbon Disulfide 

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