Several years ago one of us1 recounted the clinical history of a patient who was of interest because of the extraordinarily long period of somnolence which she had suffered and which, in combination with other signs, had led to a diagnosis of chronic lethargic encephalitis. This patient has since died, and the following pathologic study is reported because the nature and distribution of the changes represent a somewhat unusual and not well known picture of chronic encephalitis and because of the light which the observations cast on the anatomic basis of pathologic sleep.
REPORT OF CASE
—In February 1932 Patricia Maguire, aged 26, after several days of progressive drowsiness, sank into five years of almost unbroken sleep. Within twenty-four hours of the onset of her illness there were paresis of the left third cranial nerve and slight narrowing of the right visual field. During the first two
Richter RB, Traut EF. CHRONIC ENCEPHALITISPathologic Report of a Case with Protracted Somnolence. Arch NeurPsych. 1940;44(4):848-866. doi:10.1001/archneurpsyc.1940.02280100150012