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April 1941

VITAMIN THERAPY OF DISEASES OF THE NEUROMUSCULAR APPARATUS

Author Affiliations

KINGSTON, ONTARIO, CANADA; BOSTON

From the Neurological Unit, Boston City Hospital, and the Department of Neurology, Harvard Medical School.

Arch NeurPsych. 1941;45(4):672-679. doi:10.1001/archneurpsyc.1941.02280160104007
Abstract

The results which have been reported by several authors1 in the treatment of diseases of the neuromuscular apparatus by vitamins, particularly vitamin E, led us to try this treatment on 12 patients at the Boston City Hospital. While these patients have not been treated long enough to determine the ultimate effect of this therapy on the course of the disease, it was thought wise to make a report at this time.

The diagnoses in the cases in which we employed the treatment were as follows: primary degeneration of the motor neurons (progressive muscular atrophy, progressive bulbar palsy, amyotrophic lateral sclerosis), 8 cases; Erb-Landouzy scapulohumeral dystrophy, 1 case; Charcot-Marie-Tooth muscular dystrophy, 1 case; pseudohypertrophic muscular dystrophy, 1 case and amyotonia congenita, 1 case.

TECHNIC OF TREATMENT  The treatment was planned so as to give the patients the benefit of all forms of vitamin therapy that have been suggested as useful

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