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August 1941

ACUTE POSTOPERATIVE ASEPTIC LEPTOMENINGITISREVIEW OF CASES AND DISCUSSION OF PATHOGENESIS

Author Affiliations

MONTREAL, CANADA

From the Department of Neurology and Neurosurgery, McGill University, and the Montreal Neurological Institute.

Arch NeurPsych. 1941;46(2):250-276. doi:10.1001/archneurpsyc.1941.02280200056003
Abstract

The specific form of aseptic meningitis to be presented here occasionally follows operations on the central nervous system. The condition has received little attention in surgical literature, although its syndrome must have been an occasional cause for concern to all neurosurgeons of experience. When the nature and characteristics of this inflammatory process are recognized it can be readily distinguished from bacterial meningitis.

In the syndrome of acute postoperative aseptic leptomeningitis there are recurring bouts of fever, rigidity of the neck and pleocytosis. Each reaction is of sudden, dramatic onset, but of short duration, and is preceded and followed by intervals relatively free from symptoms.

The condition is troublesome rather than dangerous, for it prolongs the convalescent period by two to six weeks, without leaving serious residual complications. It occurs most often after operations in the posterior fossa which open the cisterna magna or after supratentorial operations which have left the

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