Electroencephalographic study of the human brain has not yet advanced beyond the descriptive stage. Records are described as normal or abnormal depending on their occurrence in normal control subjects or in patients with known pathologic conditions of the central nervous system. The ultimate goal of investigators in this field is to correlate the electroencephalographic patterns with neurophysiologic processes. Progress will come largely through animal experimentation and careful study of the electroencephalographic patterns associated with disorders of the central nervous system in which the location and type of lesions are known. It was with this problem in mind that the present study on neurosyphilis was begun. Furthermore, it is of practical interest to determine whether the electroencephalogram can be of any aid in the diagnosis of neurosyphilis, in the determination of the type of involvement or in the prognosis before or during the course of therapy.
This report is a
FINLEY KH, ROSE AS, SOLOMON HC. ELECTROENCEPHALOGRAPHIC STUDIES ON NEUROSYPHILIS. Arch NeurPsych. 1942;47(5):718-736. doi:10.1001/archneurpsyc.1942.02290050020002