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September 1942

WATER METABOLISM IN RELATION TO CONVULSIONSII. SPECIFIC GRAVITY OF BLOOD AND BLOOD SERUM

Author Affiliations

CHICAGO

From the Department of Nervous and Mental Diseases, Northwestern University Medical School.

Arch NeurPsych. 1942;48(3):407-416. doi:10.1001/archneurpsyc.1942.02290090063004
Abstract

Previously, one of us (T. T. S.) and an associate1 reported on a study of water balance in 18 young adults suffering from convulsions. Two of the five conclusions in the former paper will be restated here, since they led to the present study. 1. It is extremely difficult with the present methods of examination, to demonstrate a state of positive water balance in the adult human subject by excessive oral intake of fluid, even when supplemented by antidiuretic measures. 2. There was no evidence from our study to support the contention that in the adult epileptic patient the body fluid reaches a high peak just before a convulsion, drops during the seizure and rises again as a result of water retention. Furthermore, it is our opinion, expressed at that time, that either the methods for examination of body fluids were so variable as to be unsuitable for our

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