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November 1942

AMPHETAMINE SULFATE IN TREATMENT OF SPASMODIC TORTICOLLISREPORT OF TWO CASES

Author Affiliations

BOSTON

From the Division of Psychiatric Research, Boston State Hospital.

Arch NeurPsych. 1942;48(5):823-828. doi:10.1001/archneurpsyc.1942.02290110143009
Abstract

Spasmodic torticollis is a symptom complex generally considered to belong in the group of disorders of the basal ganglia, although its more exact focal pathology and pathologic physiology are obscure. It frequently occurs as an isolated involvement of the sternocleidomastoid muscle, but other muscle groups may manifest a similar disability, for example, the spinal groups of muscles and the muscle groups of the foot. Spasmodic torticollis, once well established, occurs at frequent intervals or may be practically constant, and finally contracture of the muscle may result so that the head is permanently fixed in an abnormal position. Pain and discomfort frequently accompany the spasms of the muscle groups.

The therapy of spasmodic torticollis has been on the whole unsatisfactory. Scopolamine and other sedative drugs have been used, without definite effect. Benefit in some cases has been reported from section of the spinal accessory and the upper cervical nerves. Any medication

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