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The text is divided into five parts: (1) a general introduction; (2) autonomic reactions, involving primarily the respiratory and circulatory systems; (3) autonomic-endocrine integration; (4) autonomic-somatic integration, and (5) results and applications.
In his introduction, the author states that any understanding of the physiology of the mammalian organism must obviously take into consideration the mutual relationship of the various organs and determine how any change in the external environment affects the organs of the body. This consideration of the interrelationship of organ systems in environmental adjustment the author calls the "organismic principle." The central nervous system is involved in all these conditions.
The autonomic nervous system, by altering the circulation, respiration, heat production, heat loss, changes in blood volume and erythrocyte count, protects the cortex of the brain in a most effective manner from harmful alterations in the internal environment.
The author states that the book is an experimental survey
Autonomic Regulation.. Arch NeurPsych. 1943;49(5):792. doi:10.1001/archneurpsyc.1943.02290170162016