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This is a charming little book, which reads as easily as a novel. Its perusal is recommended to the clinician, since its existence indicates that the busy clinical life is compatible with reflection, and even with research. The book records stimulating correlation of clinical and physiologic principles. The physiologist should read it, since it illuminates a few clinical problems toward the solution of which many are striving, possibly unaware of the eventual application of their own minutiae.
The main theme of the book can be most readily illustrated by the quotation of a paragraph:
"An organic lesion at the periphery, involving sensory nerve filaments, may become a source of chronic irritation. Afferent impulses from this 'trigger point' eventually create an abnormal state of activity in the internuncial neuron centers of the spinal cord gray matter. The internuncial disturbance in turn is reflected in an abnormal motor response from both the
Pain Mechanisms: A Physiologic Interpretation of Causalgia and Its Related States.. Arch NeurPsych. 1943;50(4):497. doi:10.1001/archneurpsyc.1943.02290220127013