Previous observations on patients with mental deficiencies include studies of cerebral arteriovenous oxygen differences associated with mongolism,1 cretinism,2 phenylpyruvic oligophrenia1 and undifferentiated mental deficiency.3 The purpose of the present communication is to extend these observations to patients with amaurotic familial idiocy, hydrocephalus and microcephaly. The combined data present the opportunity for comparison of the cerebral arteriovenous oxygen differences associated with the various types of mental deficiency. The methods for the collection and analysis of the cerebral arterial and venous blood are the same as those described in part I of this series.3
Amaurotic Familial Idiocy.
—Eleven observations on the cerebral arteriovenous oxygen differences for the 3 patients with amaurotic familial idiocy, between 1 to 1½ years of age, are presented in table 1. The average for 6 observations in which the arterial blood was compared with the internal jugular venous blood was 5.7 volumes
HIMWICH HE, FAZEKAS JF. CEREBRAL ARTERIOVENOUS OXYGEN DIFFERENCEII. MENTAL DEFICIENCY. Arch NeurPsych. 1944;51(1):73-77. doi:10.1001/archneurpsyc.1944.02290250079006