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January 1944

CEREBRAL CORTEX OF A MAN WITH SENILE DEMENTIA BELIEVED TO BE 107 YEARS OLD

Author Affiliations

RICHMOND, VA; WILLIAMSBURG, VA

From the Department of Neuropsychiatry, Medical College of Virginia, Richmond, Va., and the Eastern State Hospital, Williamsburg, Va.

Arch NeurPsych. 1944;51(1):78-83. doi:10.1001/archneurpsyc.1944.02290250084007
Abstract

Among the numerous publications dealing with the morphologic and histologic characteristics of the senile brain there are a few scattered cases of very old brains (Simchowicz,2 Gellerstedt3 and others). The study of these specimens, however, was included as part of a more general investigation of old brains, without particular attention to the detailed consideration of the very old brain. The results of the present studies corroborated the general observations that have been made on old brains. As far as we know, there are only 2 specimens of brains (Kuczynski4 and Aksel5) obtained from persons more than 100 years of age on which such monographic studies, based on appropriate methods,6 have been made. None of the aforementioned reports, however, deals with the problems of cortical organization which we shall consider in this study. In accordance with the more or less predominant cell type in a given

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