Headache is a prominent and important symptom following head trauma. It may appear after the slightest or the most severe injury. The seriousness of this symptom is extremely variable and is not necessarily related to the type or the degree of injury. Because of its frequent persistence long after the disappearance of other results of the injury, headache may present a difficult and distressing problem both to the patient and to the physician.
Little is known of the mechanism of traumatic headache. Among the explanations that have been offered1 are increased intracranial pressure, dilatation of the ventricular system, adhesions between the dura and the arachnoid, vasomotor instability, muscle spasm and dilatation of the arteries in the scalp and dura mater.
In this study we have attempted to approach the problem of the mechanism of post-traumatic headache by a study of its relation to the headache produced by the administration
FRIEDMAN AP, BRENNER C. POST-TRAUMATIC AND HISTAMINE HEADACHE. Arch NeurPsych. 1944;52(2):126–130. doi:10.1001/archneurpsyc.1944.02290320041005