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John Hilton, from his vast clinical experience, wrote about pain in 1876, and nearly seventy years later Sir Thomas Lewis from his vast clinical experience, wrote about pain. There is probably as much new information about pain in the volume under discussion which has accumulated in the year since the publication of Lewis' book as there was in all the years preceding.
Pain is a subjective phenomenon, and consequently does not lend itself well to animal experimentation. Hence, in the great majority of the papers collected in this volume man has been the subject of the experiments. One must pay tribute to the "pains-taking" attitude of both experimenters and subjects, since many of the experiments were obviously disagreeable and could have been carried out only for the purposes of extending the boundaries of knowledge.
New methods are ingeniously applied by means of which a sharp end point is attained, useful
Pain. Research Publications, Association for Research in Nervous and Mental Disease.. Arch NeurPsych. 1945;53(4):327–328. doi:10.1001/archneurpsyc.1945.02300040073019