MICROSCOPIC studies of the capillaries of the skin in living persons go back to 1922, when Otfried Müller, in Germany, published his book.1 His studies did not concern the subject in which I have been interested. He investigated the morphologic changes and the blood flow in capillaries of the skin in physical disease, such as disturbances of the heart and kidneys. However, he and one of his co-workers, Parrisius,2 have already described structural and functional abnormalities in so-called "vasoneurotic" patients.
The term "vasoneurotic" is somewhat vague; so no clearcut relation of the findings of these authors to the now better established types of the neuroses can be given. Some of their observations, especially on the structural abnormalities, agree with mine; others should be related, rather, to one group of neurotic patients only. However, a great many of their observations on the abnormalities of the blood flow are, according
HAUPTMANN A. CAPILLARIES IN THE FINGER NAIL FOLD IN PATIENTS WITH NEUROSIS, EPILEPSY AND MIGRAINE. Arch NeurPsych. 1946;56(6):631-642. doi:10.1001/archneurpsyc.1946.02300230025002