A certain group of patients with multiple sclerosis show personality problems at the onset or during the course of the disease. In some cases the symptoms develop or increase during periods of turmoil in interpersonal relationships. This report considers the relation of emotional conflict to the development and progress of the disease. Even after the organic changes are clearly manifest, the patient may complain of symptoms which are largely or purely functional in nature.
It has long been conceded that persons with well developed symptoms of multiple sclerosis show emotional instability. This has been explained as due to organic changes in the brain, releasing more labile emotional patterns. The syndrome of pseudobulbar palsy may be fully developed. Some years ago my colleagues and I (Langworthy, Kolb and Androp1) reported psychotic trends which appeared during the organic illness and were often severe enough to require hospitalization.
The neurologist is frequently
LANGWORTHY OR. RELATION OF PERSONALITY PROBLEMS TO ONSET AND PROGRESS OF MULTIPLE SCLEROSIS. Arch NeurPsych. 1948;59(1):13-28. doi:10.1001/archneurpsyc.1948.02300360023002